- An enzyme that goes by the name SIRTI is known to be associated with regulation of metabolic activities and also ageing and hence has become a target of therapeutics.
- A study by researchers from Tata Institute of Fundamental Research, Mumbai (TIFR) shows that glucose controls the function of SIRTI directly.
- A shortage or absence of this control can lead to a diabetic-like state, while excess feeding and sustained low levels of SIRTI can lead to obesity and enhanced ageing.
- The study was published in the Proceedings of the National Academy of Sciences.
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